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Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 13
作者:  Wang, Can;  Zhang, Shihua
收藏  |  浏览/下载:244/0  |  提交时间:2019/01/11
Epigenomics  Cell type-specific regulatory elements  Hidden Markov model  Histone modification  
Edge-group sparse PCA for network-guided high dimensional data analysis 期刊论文
BIOINFORMATICS, 2018, 卷号: 34, 期号: 20, 页码: 3479-3487
作者:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
收藏  |  浏览/下载:187/0  |  提交时间:2019/01/11
Matrix Integrative Analysis (MIA) of Multiple Genomic Data for Modular Patterns 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 12
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载:175/0  |  提交时间:2018/07/30
bioinformatics  multi-dimensional genomics  matrix integrative analysis  data integration  module discovery  non-negative matrix factorization (NMF)  partial least squares (PLS)  
Network-Regularized Sparse Logistic Regression Models for Clinical Risk Prediction and Biomarker Discovery 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 944-953
作者:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
收藏  |  浏览/下载:248/0  |  提交时间:2018/07/30
Sparse logistic regression  network-regularized penalty  survival risk prediction  feature selection  
Sparse Weighted Canonical Correlation Analysis 期刊论文
CHINESE JOURNAL OF ELECTRONICS, 2018, 卷号: 27, 期号: 3, 页码: 459-466
作者:  Min Wenwen;  Liu Juan;  Zhang Shihua
收藏  |  浏览/下载:163/0  |  提交时间:2018/07/30
Canonical correlation analysis (CCA)  Sparse canonical correlation analysis (SCCA)  Sparse weighted CCA (SWCCA)  Group LASSO regularized SWCCA  Multi-view SWCCA  
The Discovery of Mutated Driver Pathways in Cancer: Models and Algorithms 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 988-998
作者:  Zhang, Junhua;  Zhang, Shihua
收藏  |  浏览/下载:205/0  |  提交时间:2018/07/30
Bioinformatics  cancer genomics  driver gene  driver pathway  mutual exclusivity  co-occurring mutation  
MSIQ: JOINT MODELING OF MULTIPLE RNA-SEQ SAMPLES FOR ACCURATE ISOFORM QUANTIFICATION 期刊论文
ANNALS OF APPLIED STATISTICS, 2018, 卷号: 12, 期号: 1, 页码: 510-539
作者:  Li, Wei Vivian;  Zhao, Anqi;  Zhang, Shihua;  Li, Jingyi Jessica
收藏  |  浏览/下载:191/0  |  提交时间:2018/07/30
Isoform abundance estimation  joint inference from multiple samples  RNA sequencing  Bayesian hierarchical models  Gibbs sampling  data heterogeneity