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Interaction-based transcriptome analysis via differential network inference 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 11
作者:  Leng, Jiacheng;  Wu, Ling-Yun
收藏  |  浏览/下载:47/0  |  提交时间:2023/02/07
differential network inference  differential expression analysis  interaction-based transcriptome analysis  
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:  Lu, Yong;  Xue, Gang;  Zheng, Ningbo;  Han, Kun;  Yang, Wenzhong;  Wang, Rui-Sheng;  Wu, Lingyun;  Miller, Lance D.;  Pardee, Timothy;  Triozzi, Pierre L.;  Lo, Hui-Wen;  Watabe, Kounosuke;  Wong, Stephen T. C.;  Pasche, Boris C.;  Zhang, Wei;  Jin, Guangxu
收藏  |  浏览/下载:125/0  |  提交时间:2023/02/07
single-cell RNA sequencing (scRNA-seq)  single-cell mass cytometry (CyTOF)  Pareto optimization  projection-free single-cell modeling  response to immune checkpoint blockade  
Importance-Penalized Joint Graphical Lasso (IPJGL): differential network inference via GGMs 期刊论文
BIOINFORMATICS, 2022, 卷号: 38, 期号: 3, 页码: 770-777
作者:  Leng, Jiacheng;  Wu, Ling-Yun
收藏  |  浏览/下载:143/0  |  提交时间:2022/04/02
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data 期刊论文
NATURE BIOTECHNOLOGY, 2021, 页码: 18
作者:  Sun, Duanchen;  Guan, Xiangnan;  Moran, Amy E.;  Wu, Ling-Yun;  Qian, David Z.;  Schedin, Pepper;  Dai, Mu-Shui;  Danilov, Alexey, V;  Alumkal, Joshi J.;  Adey, Andrew C.;  Spellman, Paul T.;  Xia, Zheng
收藏  |  浏览/下载:145/0  |  提交时间:2022/04/02
Identification of Common Driver Gene Modules and Associations between Cancers through Integrated Network Analysis 期刊论文
GLOBAL CHALLENGES, 2021, 页码: 13
作者:  Gao, Bo;  Zhao, Yue;  Gao, Yonghang;  Li, Guojun;  Wu, Ling-Yun
收藏  |  浏览/下载:189/0  |  提交时间:2021/10/26
driver gene module  gene mutation  mutual exclusivity  network analysis  signaling pathway  
Framework and algorithms for identifying honest blocks in blockchain 期刊论文
PLOS ONE, 2020, 卷号: 15, 期号: 1, 页码: 14
作者:  Wang, Xu;  Gan, Guohua;  Wu, Ling-Yun
收藏  |  浏览/下载:185/0  |  提交时间:2020/06/30
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
收藏  |  浏览/下载:293/0  |  提交时间:2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression  
CEA: Combination-based gene set functional enrichment analysis 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 13
作者:  Sun, Duanchen;  Liu, Yinliang;  Zhang, Xiang-Sun;  Wu, Ling-Yun
收藏  |  浏览/下载:255/0  |  提交时间:2018/10/07
NetGen: a novel network-based probabilistic generative model for gene set functional enrichment analysis 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 14
作者:  Sun, Duanchen;  Liu, Yinliang;  Zhang, Xiang-Sun;  Wu, Ling-Yun
收藏  |  浏览/下载:134/0  |  提交时间:2018/07/30
Gene ontology  Enrichment analysis  Network-based probabilistic generative model  Integer programming  Complex diseases  
Gly-PseAAC: Identifying protein lysine glycation through sequences 期刊论文
GENE, 2017, 卷号: 602, 页码: 1-7
作者:  Xu, Yan;  Li, Li;  Ding, Jun;  Wu, Ling-Yun;  Mai, Guoqin;  Zhou, Fengfeng
收藏  |  浏览/下载:163/0  |  提交时间:2018/07/30
Glycation  Amino acid propensity  Support Vector Machine