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Integrating data- and model-driven strategies in systems biology INTRODUCTION 期刊论文
BMC SYSTEMS BIOLOGY, 2018, 卷号: 12, 页码: 3
作者:  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载:174/0  |  提交时间:2018/07/30
Integrating data- and model-driven strategies in systems biology 期刊论文
BMC Systems Biology, 2018, 卷号: 12, 期号: Suppl 4
作者:  Wang,Yong;  Zhang,Xiang-Sun;  Chen,Luonan
收藏  |  浏览/下载:199/0  |  提交时间:2018/07/30
NetGen: a novel network-based probabilistic generative model for gene set functional enrichment analysis 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 14
作者:  Sun, Duanchen;  Liu, Yinliang;  Zhang, Xiang-Sun;  Wu, Ling-Yun
收藏  |  浏览/下载:131/0  |  提交时间:2018/07/30
Gene ontology  Enrichment analysis  Network-based probabilistic generative model  Integer programming  Complex diseases  
Hybrid method to solve HP model on 3D lattice and to probe protein stability upon amino acid mutations 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 13
作者:  Guo, Yuzhen;  Tao, Fengying;  Wu, Zikai;  Wang, Yong
收藏  |  浏览/下载:157/0  |  提交时间:2018/07/30
Protein structure prediction  HP model  3D lattice  Particle swarm optimization  Protein stability  
Understanding biological systems through the lens of data 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 2
作者:  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载:149/0  |  提交时间:2018/07/30
Improved protein-protein interactions prediction via weighted sparse representation model combining continuous wavelet descriptor and PseAA composition 期刊论文
BMC SYSTEMS BIOLOGY, 2016, 卷号: 10, 页码: 10
作者:  Huang, Yu-An;  You, Zhu-Hong;  Chen, Xing;  Yan, Gui-Ying
收藏  |  浏览/下载:160/0  |  提交时间:2018/07/30
Protein-protein interactions  Protein sequence  Continuous wavelet transform  Sparse representation based classifier  
Stochastic modeling suggests that noise reduces differentiation efficiency by inducing a heterogeneous drug response in glioma differentiation therapy 期刊论文
BMC Systems Biology, 2016, 卷号: 10, 期号: 1
作者:  Sun,Xiaoqiang;  Zhang,Jiajun;  Zhao,Qi;  Chen,Xing;  Zhu,Wenbo;  Yan,Guangmei;  Zhou,Tianshou
收藏  |  浏览/下载:126/0  |  提交时间:2018/07/30
Stochastic modeling  Ultrasensitivity  Noise  Differentiation efficiency  Drug resistance  Glioma differentiation therapy  
Corbi: a new R package for biological network alignment and querying 期刊论文
BMC Systems Biology, 2013, 卷号: 7, 期号: Suppl 2
作者:  Huang,Qiang;  Wu,Ling-Yun;  Zhang,Xiang-Sun
收藏  |  浏览/下载:145/0  |  提交时间:2018/07/30
Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data 期刊论文
BMC Systems Biology, 2013, 卷号: 7, 期号: Suppl 2
作者:  Zhang,Junhua;  Zhang,Shihua;  Wang,Yong;  Zhang,Xiang-Sun
收藏  |  浏览/下载:139/0  |  提交时间:2018/07/30
Computational systems biology in the big data era 期刊论文
BMC Systems Biology, 2013, 卷号: 7, 期号: Suppl 2
作者:  Wang,Yong;  Zhang,Xiang-Sun;  Chen,Luonan
收藏  |  浏览/下载:145/0  |  提交时间:2018/07/30