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hReg-CNCC reconstructs a regulatory network in human cranial neural crest cells and annotates variants in a developmental context 期刊论文
COMMUNICATIONS BIOLOGY, 2021, 卷号: 4, 期号: 1, 页码: 16
作者:  Feng, Zhanying;  Duren, Zhana;  Xiong, Ziyi;  Wang, Sijia;  Liu, Fan;  Wong, Wing Hung;  Wang, Yong
收藏  |  浏览/下载:180/0  |  提交时间:2021/06/01
Integrating distal and proximal information to predict gene expression via a densely connected convolutional neural network 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 2, 页码: 496-503
作者:  Zeng, Wanwen;  Wang, Yong;  Jiang, Rui
收藏  |  浏览/下载:167/0  |  提交时间:2020/06/30
Hierarchical graphical model reveals HFR1 bridging circadian rhythm and flower development in Arabidopsis thaliana 期刊论文
NPJ SYSTEMS BIOLOGY AND APPLICATIONS, 2019, 卷号: 5, 页码: 11
作者:  Duren, Zhana;  Wang, Yaling;  Wang, Jiguang;  Zhao, Xing-Ming;  Lv, Le;  Li, Xiaobo;  Liu, Jingdong;  Zhu, Xin-Guang;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载:168/0  |  提交时间:2020/05/24
Modeling gene regulation from paired expression and chromatin accessibility data 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 25, 页码: E4914-E4923
作者:  Duren, Zhana;  Chen, Xi;  Jiang, Rui;  Wang, Yong;  Wong, Wing Hung
收藏  |  浏览/下载:159/0  |  提交时间:2018/07/30
gene regulation  transcription factor  regulatory element  chromatin regulator  chromatin activity  
Predicting transcription factor binding motifs from DNA-binding domains, chromatin accessibility and gene expression data 期刊论文
NUCLEIC ACIDS RESEARCH, 2017, 卷号: 45, 期号: 10, 页码: 5666-5677
作者:  Zamanighomi, Mahdi;  Lin, Zhixiang;  Wang, Yong;  Jiang, Rui;  Wong, Wing Hung
收藏  |  浏览/下载:146/0  |  提交时间:2018/07/30
Modeling the causal regulatory network by integrating chromatin accessibility and transcriptome data 期刊论文
NATIONAL SCIENCE REVIEW, 2016, 卷号: 3, 期号: 2, 页码: 240-251
作者:  Wang, Yong;  Jiang, Rui;  Wong, Wing Hung
收藏  |  浏览/下载:123/0  |  提交时间:2018/07/30
gene regulatory network  open chromatin  DNA accessibility  transcription factor colocalization  statistical model  data integration  
Computational probing protein-protein interactions targeting small molecules 期刊论文
BIOINFORMATICS, 2016, 卷号: 32, 期号: 2, 页码: 226-234
作者:  Wang, Yong-Cui;  Chen, Shi-Long;  Deng, Nai-Yang;  Wang, Yong
收藏  |  浏览/下载:134/0  |  提交时间:2018/07/30
Prediction of protein-RNA binding sites by a random forest method with combined features 期刊论文
BIOINFORMATICS, 2010, 卷号: 26, 期号: 13, 页码: 1616-1622
作者:  Liu, Zhi-Ping;  Wu, Ling-Yun;  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载:144/0  |  提交时间:2018/07/30
Computationally Probing Drug-Protein Interactions Via Support Vector Machine 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2010, 卷号: 7, 期号: 5, 页码: 370-378
作者:  Wang, Yong-Cui;  Yang, Zhi-Xia;  Wang, Yong;  Deng, Nai-Yang
收藏  |  浏览/下载:118/0  |  提交时间:2018/07/30
Drug-target interaction  Chemical structure  Protein sequence  Imbalance problem  Support vector machine  
Identifying translation initiation sites in prokaryotes using support vector machine 期刊论文
JOURNAL OF THEORETICAL BIOLOGY, 2010, 卷号: 262, 期号: 4, 页码: 644-649
作者:  Gao, Tingting;  Yang, Zhixia;  Wang, Yong;  Jing, Ling
收藏  |  浏览/下载:126/0  |  提交时间:2018/07/30
Translation initiation site prediction  Support vector machine  Position specific weight matrix