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Prediction of enhancer-promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 16
作者:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
收藏  |  浏览/下载:137/0  |  提交时间:2021/01/14
Enhancer–  promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Prediction of enhancer–promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC Bioinformatics, 2020, 卷号: 21, 期号: 1
作者:  Jing,Fang;  Zhang,Shao-Wu;  Zhang,Shihua
收藏  |  浏览/下载:140/0  |  提交时间:2021/01/14
Enhancer–promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 13
作者:  Wang, Can;  Zhang, Shihua
收藏  |  浏览/下载:244/0  |  提交时间:2019/01/11
Epigenomics  Cell type-specific regulatory elements  Hidden Markov model  Histone modification  
MSIQ: JOINT MODELING OF MULTIPLE RNA-SEQ SAMPLES FOR ACCURATE ISOFORM QUANTIFICATION 期刊论文
ANNALS OF APPLIED STATISTICS, 2018, 卷号: 12, 期号: 1, 页码: 510-539
作者:  Li, Wei Vivian;  Zhao, Anqi;  Zhang, Shihua;  Li, Jingyi Jessica
收藏  |  浏览/下载:191/0  |  提交时间:2018/07/30
Isoform abundance estimation  joint inference from multiple samples  RNA sequencing  Bayesian hierarchical models  Gibbs sampling  data heterogeneity  
Integrative Analysis of Transcription Factor Combinatorial Interactions Using a Bayesian Tensor Factorization Approach 期刊论文
FRONTIERS IN GENETICS, 2017, 卷号: 8, 页码: 12
作者:  Ye, Yusen;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载:144/0  |  提交时间:2018/07/30
transcription regulation  TF regulatory networks  tensor factorization  integrative analysis of omics data  biological networks  
Large-scale determination and characterization of cell type-specific regulatory elements in the human genome 期刊论文
Journal of Molecular Cell Biology, 2017, 卷号: 9, 期号: 6, 页码: 463
作者:  Wang Can;  Zhang Shihua
收藏  |  浏览/下载:142/0  |  提交时间:2018/07/30
Comparative DNA methylation analysis to decipher common and cell type-specific patterns among multiple cell types 期刊论文
BRIEFINGS IN FUNCTIONAL GENOMICS, 2016, 卷号: 15, 期号: 6, 页码: 399-407
作者:  Yang, Xiaofei;  Shao, Xiaojian;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载:156/0  |  提交时间:2018/07/30
DNA methylation patterns  differentially methylation regions  comparative studies  tissue-specific methylation  cancer epigenomics  
An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 13
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载:130/0  |  提交时间:2018/07/30
A Two-Stage Method to Identify Joint Modules From Matched MicroRNA and mRNA Expression Data 期刊论文
IEEE TRANSACTIONS ON NANOBIOSCIENCE, 2016, 卷号: 15, 期号: 4, 页码: 362-370
作者:  Min, Wenwen;  Liu, Juan;  Luo, Fei;  Zhang, Shihua
收藏  |  浏览/下载:164/0  |  提交时间:2018/07/30
L-0-penalized singular value decomposition (L-0-SVD)  miRNA cluster  miRNA-gene joint module  multiple-output sparse group lasso  
promoteconnectionsofyoungcomputationalbiologistsinchina 期刊论文
genomicsproteomicsbioinformatics, 2013, 卷号: 11, 期号: 4, 页码: 253
作者:  Zhang Shihua;  Wang Xiujie
收藏  |  浏览/下载:127/0  |  提交时间:2020/01/10