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hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:  Lu, Yong;  Xue, Gang;  Zheng, Ningbo;  Han, Kun;  Yang, Wenzhong;  Wang, Rui-Sheng;  Wu, Lingyun;  Miller, Lance D.;  Pardee, Timothy;  Triozzi, Pierre L.;  Lo, Hui-Wen;  Watabe, Kounosuke;  Wong, Stephen T. C.;  Pasche, Boris C.;  Zhang, Wei;  Jin, Guangxu
收藏  |  浏览/下载:120/0  |  提交时间:2023/02/07
single-cell RNA sequencing (scRNA-seq)  single-cell mass cytometry (CyTOF)  Pareto optimization  projection-free single-cell modeling  response to immune checkpoint blockade  
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
收藏  |  浏览/下载:285/0  |  提交时间:2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression  
Gly-PseAAC: Identifying protein lysine glycation through sequences 期刊论文
GENE, 2017, 卷号: 602, 页码: 1-7
作者:  Xu, Yan;  Li, Li;  Ding, Jun;  Wu, Ling-Yun;  Mai, Guoqin;  Zhou, Fengfeng
收藏  |  浏览/下载:157/0  |  提交时间:2018/07/30
Glycation  Amino acid propensity  Support Vector Machine  
Mal-Lys: prediction of lysine malonylation sites in proteins integrated sequence-based features with mRMR feature selection 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 7
作者:  Xu, Yan;  Ding, Ya-Xin;  Ding, Jun;  Wu, Ling-Yun;  Xue, Yu
收藏  |  浏览/下载:132/0  |  提交时间:2018/07/30
iSulf-Cys: Prediction of S-sulfenylation Sites in Proteins with Physicochemical Properties of Amino Acids 期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 4, 页码: 9
作者:  Xu, Yan;  Ding, Jun;  Wu, Ling-Yun
收藏  |  浏览/下载:117/0  |  提交时间:2018/07/30
Phogly-PseAAC: Prediction of lysine phosphoglycerylation in proteins incorporating with position-specific propensity 期刊论文
JOURNAL OF THEORETICAL BIOLOGY, 2015, 卷号: 379, 页码: 10-15
作者:  Xu, Yan;  Ding, Ya-Xin;  Ding, Jun;  Wu, Ling-Yun;  Deng, Nai-Yang
收藏  |  浏览/下载:132/0  |  提交时间:2018/07/30
Amino acid propensity  F-score  Phosphoglycerylation  
Semi-supervised drug-protein interaction prediction from heterogeneous biological spaces 期刊论文
BMC SYSTEMS BIOLOGY, 2010, 卷号: 4, 页码: 12
作者:  Xia, Zheng;  Wu, Ling-Yun;  Zhou, Xiaobo;  Wong, Stephen T. C.
收藏  |  浏览/下载:129/0  |  提交时间:2018/07/30
Prediction of protein-RNA binding sites by a random forest method with combined features 期刊论文
BIOINFORMATICS, 2010, 卷号: 26, 期号: 13, 页码: 1616-1622
作者:  Liu, Zhi-Ping;  Wu, Ling-Yun;  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载:142/0  |  提交时间:2018/07/30
Lysine acetylation sites prediction using an ensemble of support vector machine classifiers 期刊论文
JOURNAL OF THEORETICAL BIOLOGY, 2010, 卷号: 264, 期号: 1, 页码: 130-135
作者:  Xu, Yan;  Wang, Xiao-Bo;  Ding, Jun;  Wu, Ling-Yun;  Deng, Nai-Yang
收藏  |  浏览/下载:125/0  |  提交时间:2018/07/30
Bioinformatics  Acetylated proteins  Ensemble  SVM  PWMs  EnsemblePail  
Prediction of palmitoylation sites using the composition of k-spaced amino acid pairs 期刊论文
PROTEIN ENGINEERING DESIGN & SELECTION, 2009, 卷号: 22, 期号: 11, 页码: 707-712
作者:  Wang, Xiao-Bo;  Wu, Ling-Yun;  Wang, Yong-Cui;  Deng, Nai-Yang
收藏  |  浏览/下载:112/0  |  提交时间:2018/07/30
CKSAAP-Palm  palmitoylated proteins  palmitoylation  support vector machine