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Interaction-based transcriptome analysis via differential network inference 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 11
作者:  Leng, Jiacheng;  Wu, Ling-Yun
收藏  |  浏览/下载:47/0  |  提交时间:2023/02/07
differential network inference  differential expression analysis  interaction-based transcriptome analysis  
Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis 期刊论文
NATIONAL SCIENCE REVIEW, 2022, 卷号: 9, 期号: 7, 页码: 15
作者:  Jin, Yujuan;  Zhao, Qiqi;  Zhu, Weikang;  Feng, Yan;  Xiao, Tian;  Zhang, Peng;  Jiang, Liyan;  Hou, Yingyong;  Guo, Chenchen;  Huang, Hsinyi;  Chen, Yabin;  Tong, Xinyuan;  Cao, Jiayu;  Li, Fei;  Zhu, Xueliang;  Qin, Jun;  Gao, Dong;  Liu, Xin-Yuan;  Zhang, Hua;  Chen, Luonan;  Thomas, Roman K.;  Wong, Kwok-Kin;  Zhang, Lei;  Wang, Yong;  Hu, Liang;  Ji, Hongbin
收藏  |  浏览/下载:82/0  |  提交时间:2023/02/07
small cell lung cancer  SWI  SNF complex  TAZ  phenotypic transition  metastasis  
Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:  Shi, Xiaohan;  Li, Yunguang;  Yuan, Qiuyue;  Tang, Shijie;  Guo, Shiwei;  Zhang, Yehan;  He, Juan;  Zhang, Xiaoyu;  Han, Ming;  Liu, Zhuang;  Zhu, Yiqin;  Gao, Suizhi;  Wang, Huan;  Xu, Xiongfei;  Zheng, Kailian;  Jing, Wei;  Chen, Luonan;  Wang, Yong;  Jin, Gang;  Gao, Dong
收藏  |  浏览/下载:127/0  |  提交时间:2022/06/21
BiTSC2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 12
作者:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
收藏  |  浏览/下载:159/0  |  提交时间:2022/06/21
single-cell DNA sequencing  intra-tumor heterogeneity  single nucleotide variation  copy number alteration  Bayesian modeling  cancer evolution  
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:  Lu, Yong;  Xue, Gang;  Zheng, Ningbo;  Han, Kun;  Yang, Wenzhong;  Wang, Rui-Sheng;  Wu, Lingyun;  Miller, Lance D.;  Pardee, Timothy;  Triozzi, Pierre L.;  Lo, Hui-Wen;  Watabe, Kounosuke;  Wong, Stephen T. C.;  Pasche, Boris C.;  Zhang, Wei;  Jin, Guangxu
收藏  |  浏览/下载:120/0  |  提交时间:2023/02/07
single-cell RNA sequencing (scRNA-seq)  single-cell mass cytometry (CyTOF)  Pareto optimization  projection-free single-cell modeling  response to immune checkpoint blockade  
Importance-Penalized Joint Graphical Lasso (IPJGL): differential network inference via GGMs 期刊论文
BIOINFORMATICS, 2022, 卷号: 38, 期号: 3, 页码: 770-777
作者:  Leng, Jiacheng;  Wu, Ling-Yun
收藏  |  浏览/下载:141/0  |  提交时间:2022/04/02
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data 期刊论文
NATURE BIOTECHNOLOGY, 2021, 页码: 18
作者:  Sun, Duanchen;  Guan, Xiangnan;  Moran, Amy E.;  Wu, Ling-Yun;  Qian, David Z.;  Schedin, Pepper;  Dai, Mu-Shui;  Danilov, Alexey, V;  Alumkal, Joshi J.;  Adey, Andrew C.;  Spellman, Paul T.;  Xia, Zheng
收藏  |  浏览/下载:138/0  |  提交时间:2022/04/02
Approximate distance correlation for selecting highly interrelated genes across datasets 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 11, 页码: 18
作者:  Shen, Qunlun;  Zhang, Shihua
收藏  |  浏览/下载:116/0  |  提交时间:2022/04/02
On estimating optimal regime for treatment initiation time based on restricted mean residual lifetime 期刊论文
BIOMETRICS, 2021, 页码: 13
作者:  Chen, Xin;  Song, Rui;  Zhang, Jiajia;  Adams, Swann Arp;  Sun, Liuquan;  Lu, Wenbin
收藏  |  浏览/下载:150/0  |  提交时间:2021/10/26
individualized treatment regime  kernel estimation  optimal treatment initiation time  time-to-event data  value function  
Multiple-Tissue and Multilevel Analysis on Differentially Expressed Genes and Differentially Correlated Gene Pairs for HFpEF 期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 页码: 14
作者:  Zhou, Guofeng;  Sun, Shaoyan;  Yuan, Qiuyue;  Zhang, Run;  Jiang, Ping;  Li, Guangyu;  Wang, Yong;  Li, Xiao
收藏  |  浏览/下载:127/0  |  提交时间:2021/10/26
heart failure with preserved ejection fraction  differentially expressed genes  differentially correlated gene pairs  differential network  molecular docking