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RobustClone: a robust PCA method for tumor clone and evolution inference from single-cell sequencing data 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 11, 页码: 3299-3306
作者:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
收藏  |  浏览/下载:168/0  |  提交时间:2020/09/23
Prediction of Driver Modules via Balancing Exclusive Coverages of Mutations in Cancer Samples 期刊论文
ADVANCED SCIENCE, 2019, 卷号: 6, 期号: 4, 页码: 9
作者:  Gao, Bo;  Zhao, Yue;  Li, Yang;  Liu, Juntao;  Wang, Lushan;  Li, Guojun;  Su, Zhengchang
收藏  |  浏览/下载:196/0  |  提交时间:2019/04/02
cancer genomics  coverage  driver modules  exclusivity  signaling networks  
Prediction of subcellular location of apoptosis proteins by incorporating PsePSSM and DCCA coefficient based on LFDA dimensionality reduction 期刊论文
BMC Genomics, 2018, 卷号: 19, 期号: 1
作者:  Yu,Bin;  Li,Shan;  Qiu,Wenying;  Wang,Minghui;  Du,Junwei;  Zhang,Yusen;  Chen,Xing
收藏  |  浏览/下载:175/0  |  提交时间:2018/07/30
Apoptosis proteins  Subcellular localization  Pseudo-position specific scoring matrix  Detrended cross-correlation analysis coefficient  Local fisher discriminant analysis  Support vector machine  
The Discovery of Mutated Driver Pathways in Cancer: Models and Algorithms 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 988-998
作者:  Zhang, Junhua;  Zhang, Shihua
收藏  |  浏览/下载:205/0  |  提交时间:2018/07/30
Bioinformatics  cancer genomics  driver gene  driver pathway  mutual exclusivity  co-occurring mutation  
Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2017, 卷号: 18, 期号: 5, 页码: 761-773
作者:  Yang, Xiaofei;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载:136/0  |  提交时间:2018/07/30
cancer genomics  DNA-methylation  pan-cancer study  bioinformatics  
Integrative cancer genomics: models, algorithms and analysis 期刊论文
FRONTIERS OF COMPUTER SCIENCE, 2017, 卷号: 11, 期号: 3, 页码: 392-406
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载:132/0  |  提交时间:2018/07/30
cancer genomics  model  algorithm  data integration  bioinformatics  computational biology  
integrativecancergenomicsmodelsalgorithmsandanalysis 期刊论文
frontiersofcomputerscience, 2017, 卷号: 11, 期号: 3, 页码: 392
作者:  Chen Jinyu;  Zhang Shihua
收藏  |  浏览/下载:123/0  |  提交时间:2020/01/10
Comparative DNA methylation analysis to decipher common and cell type-specific patterns among multiple cell types 期刊论文
BRIEFINGS IN FUNCTIONAL GENOMICS, 2016, 卷号: 15, 期号: 6, 页码: 399-407
作者:  Yang, Xiaofei;  Shao, Xiaojian;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载:158/0  |  提交时间:2018/07/30
DNA methylation patterns  differentially methylation regions  comparative studies  tissue-specific methylation  cancer epigenomics  
Tumor characterization and stratification by integrated molecular profiles reveals essential pan-cancer features 期刊论文
BMC GENOMICS, 2015, 卷号: 16, 页码: 12
作者:  Liu, Zhaoqi;  Zhang, Shihua
收藏  |  浏览/下载:145/0  |  提交时间:2018/07/30
Identifying network biomarkers based on protein-protein interactions and expression data 期刊论文
BMC MEDICAL GENOMICS, 2015, 卷号: 8, 页码: 11
作者:  Xin, Jingxue;  Ren, Xianwen;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载:122/0  |  提交时间:2018/07/30