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中国科学院数学与系统科学研究院机构知识库
KMS Of Academy of mathematics and systems sciences, CAS
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Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis
期刊论文
NATIONAL SCIENCE REVIEW, 2022, 卷号: 9, 期号: 7, 页码: 15
作者:
Jin, Yujuan
;
Zhao, Qiqi
;
Zhu, Weikang
;
Feng, Yan
;
Xiao, Tian
;
Zhang, Peng
;
Jiang, Liyan
;
Hou, Yingyong
;
Guo, Chenchen
;
Huang, Hsinyi
;
Chen, Yabin
;
Tong, Xinyuan
;
Cao, Jiayu
;
Li, Fei
;
Zhu, Xueliang
;
Qin, Jun
;
Gao, Dong
;
Liu, Xin-Yuan
;
Zhang, Hua
;
Chen, Luonan
;
Thomas, Roman K.
;
Wong, Kwok-Kin
;
Zhang, Lei
;
Wang, Yong
;
Hu, Liang
;
Ji, Hongbin
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2023/02/07
small cell lung cancer
SWI
SNF complex
TAZ
phenotypic transition
metastasis
Deciphering the Spatial Modular Patterns of Tissues by Integrating Spatial and Single-Cell Transcriptomic Data
期刊论文
JOURNAL OF COMPUTATIONAL BIOLOGY, 2022, 页码: 14
作者:
Shan, Xu
;
Chen, Jinyu
;
Dong, Kangning
;
Zhou, Wei
;
Zhang, Shihua
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2023/02/07
data integration
single-cell transcriptomics
spatial modular patterns
spatial transcriptomics
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:
Lu, Yong
;
Xue, Gang
;
Zheng, Ningbo
;
Han, Kun
;
Yang, Wenzhong
;
Wang, Rui-Sheng
;
Wu, Lingyun
;
Miller, Lance D.
;
Pardee, Timothy
;
Triozzi, Pierre L.
;
Lo, Hui-Wen
;
Watabe, Kounosuke
;
Wong, Stephen T. C.
;
Pasche, Boris C.
;
Zhang, Wei
;
Jin, Guangxu
收藏
  |  
浏览/下载:120/0
  |  
提交时间:2023/02/07
single-cell RNA sequencing (scRNA-seq)
single-cell mass cytometry (CyTOF)
Pareto optimization
projection-free single-cell modeling
response to immune checkpoint blockade
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
期刊论文
NATURE BIOTECHNOLOGY, 2021, 页码: 18
作者:
Sun, Duanchen
;
Guan, Xiangnan
;
Moran, Amy E.
;
Wu, Ling-Yun
;
Qian, David Z.
;
Schedin, Pepper
;
Dai, Mu-Shui
;
Danilov, Alexey, V
;
Alumkal, Joshi J.
;
Adey, Andrew C.
;
Spellman, Paul T.
;
Xia, Zheng
收藏
  |  
浏览/下载:138/0
  |  
提交时间:2022/04/02
A kernel non-negative matrix factorization framework for single cell clustering
期刊论文
APPLIED MATHEMATICAL MODELLING, 2021, 卷号: 90, 页码: 875-888
作者:
Jiang, Hao
;
Yi, Ming
;
Zhang, Shihua
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2021/04/26
Single cell RNA-sequencing
Kernel non-negative matrix factorization
Cellular heterogeneity
Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts
期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
作者:
Zhang, Lihua
;
Zhang, Shihua
收藏
  |  
浏览/下载:125/0
  |  
提交时间:2021/10/26
single-cell RNA-seq
dropout
imputation
low-rank
systems biology
NeuralEE: A GPU-Accelerated Elastic Embedding Dimensionality Reduction Method for Visualizing Large-Scale scRNA-Seq Data
期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 8
作者:
Xiong, Jiankang
;
Gong, Fuzhou
;
Wan, Lin
;
Ma, Liang
收藏
  |  
浏览/下载:165/0
  |  
提交时间:2021/01/14
single-cell RNA sequencing
elastic embedding
neural networks
large-scale
stochastic optimization
parametric models
generalizable models
Comparison of Computational Methods for Imputing Single-Cell RNA-Sequencing Data
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 376-389
作者:
Zhang, Lihua
;
Zhang, Shihua
收藏
  |  
浏览/下载:161/0
  |  
提交时间:2020/05/24
Gene expression
Sequential analysis
Bioinformatics
RNA
Matrix converters
Computational biology
Bayes methods
Single-cell RNA-sequencing technique
dropout event
imputation
algorithm
bioinformatics
ELF: Extract Landmark Features By Optimizing Topology Maintenance, Redundancy, and Specificity
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 411-421
作者:
Feng, Zhan-Ying
;
Wang, Yong
收藏
  |  
浏览/下载:179/0
  |  
提交时间:2020/05/24
Feature extraction
Topology
Ground penetrating radar
Geophysical measurement techniques
Redundancy
Maintenance engineering
Manganese
Feature selection
topology maintenance
optimization
single cell
DensityPath: an algorithm to visualize and reconstruct cell state-transition path on density landscape for single-cell RNA sequencing data
期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 15, 页码: 2593-2601
作者:
Chen, Ziwei
;
An, Shaokun
;
Bai, Xiangqi
;
Gong, Fuzhou
;
Ma, Liang
;
Wan, Lin
收藏
  |  
浏览/下载:190/0
  |  
提交时间:2020/01/10