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Annotating regulatory elements by heterogeneous network embedding 期刊论文
BIOINFORMATICS, 2022, 页码: 13
作者:  Lu, Yurun;  Feng, Zhanying;  Zhang, Songmao;  Wang, Yong
收藏  |  浏览/下载:139/0  |  提交时间:2022/06/21
MIMIC: an optimization method to identify cell type-specific marker panel for cell sorting 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 6, 页码: 14
作者:  Zou, Meng;  Duren, Zhana;  Yuan, Qiuyue;  Li, Henry;  Hutchins, Andrew Paul;  Wong, Wing Hung;  Wang, Yong
收藏  |  浏览/下载:145/0  |  提交时间:2022/04/02
cell type-specific marker  TFs  surface markers  dimension reduction  hierarchical topology  
Approximate distance correlation for selecting highly interrelated genes across datasets 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 11, 页码: 18
作者:  Shen, Qunlun;  Zhang, Shihua
收藏  |  浏览/下载:116/0  |  提交时间:2022/04/02
Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:129/0  |  提交时间:2021/10/26
single-cell RNA-seq  dropout  imputation  low-rank  systems biology  
Comparison of Computational Methods for Imputing Single-Cell RNA-Sequencing Data 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 376-389
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:164/0  |  提交时间:2020/05/24
Gene expression  Sequential analysis  Bioinformatics  RNA  Matrix converters  Computational biology  Bayes methods  Single-cell RNA-sequencing technique  dropout event  imputation  algorithm  bioinformatics  
ELF: Extract Landmark Features By Optimizing Topology Maintenance, Redundancy, and Specificity 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 411-421
作者:  Feng, Zhan-Ying;  Wang, Yong
收藏  |  浏览/下载:185/0  |  提交时间:2020/05/24
Feature extraction  Topology  Ground penetrating radar  Geophysical measurement techniques  Redundancy  Maintenance engineering  Manganese  Feature selection  topology maintenance  optimization  single cell  
Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 12, 页码: 20
作者:  Wang, Yongcui;  Chen, Shilong;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载:185/0  |  提交时间:2020/05/24
Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 13, 页码: 6606-6617
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:192/0  |  提交时间:2020/01/10
MSIQ: JOINT MODELING OF MULTIPLE RNA-SEQ SAMPLES FOR ACCURATE ISOFORM QUANTIFICATION 期刊论文
ANNALS OF APPLIED STATISTICS, 2018, 卷号: 12, 期号: 1, 页码: 510-539
作者:  Li, Wei Vivian;  Zhao, Anqi;  Zhang, Shihua;  Li, Jingyi Jessica
收藏  |  浏览/下载:194/0  |  提交时间:2018/07/30
Isoform abundance estimation  joint inference from multiple samples  RNA sequencing  Bayesian hierarchical models  Gibbs sampling  data heterogeneity