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Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载：125/0  |  提交时间：2021/10/26
single-cell RNA-seq  dropout  imputation  low-rank  systems biology  
Comparison of Computational Methods for Imputing Single-Cell RNA-Sequencing Data 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 376-389
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载：161/0  |  提交时间：2020/05/24
Gene expression  Sequential analysis  Bioinformatics  RNA  Matrix converters  Computational biology  Bayes methods  Single-cell RNA-sequencing technique  dropout event  imputation  algorithm  bioinformatics  
ELF: Extract Landmark Features By Optimizing Topology Maintenance, Redundancy, and Specificity 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 411-421
作者:  Feng, Zhan-Ying;  Wang, Yong
收藏  |  浏览/下载：178/0  |  提交时间：2020/05/24
Feature extraction  Topology  Ground penetrating radar  Geophysical measurement techniques  Redundancy  Maintenance engineering  Manganese  Feature selection  topology maintenance  optimization  single cell  
MSIQ: JOINT MODELING OF MULTIPLE RNA-SEQ SAMPLES FOR ACCURATE ISOFORM QUANTIFICATION 期刊论文
ANNALS OF APPLIED STATISTICS, 2018, 卷号: 12, 期号: 1, 页码: 510-539
作者:  Li, Wei Vivian;  Zhao, Anqi;  Zhang, Shihua;  Li, Jingyi Jessica
收藏  |  浏览/下载：191/0  |  提交时间：2018/07/30
Isoform abundance estimation  joint inference from multiple samples  RNA sequencing  Bayesian hierarchical models  Gibbs sampling  data heterogeneity