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Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:  Shi, Xiaohan;  Li, Yunguang;  Yuan, Qiuyue;  Tang, Shijie;  Guo, Shiwei;  Zhang, Yehan;  He, Juan;  Zhang, Xiaoyu;  Han, Ming;  Liu, Zhuang;  Zhu, Yiqin;  Gao, Suizhi;  Wang, Huan;  Xu, Xiongfei;  Zheng, Kailian;  Jing, Wei;  Chen, Luonan;  Wang, Yong;  Jin, Gang;  Gao, Dong
收藏  |  浏览/下载：128/0  |  提交时间：2022/06/21
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3, 页码: 15
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载：115/0  |  提交时间：2022/04/02
cis-regulatory interaction networks  single-cell ATAC-seq  Gaussian graphical LASSO  
An Integrative Framework for Combining Sequence and Epigenomic Data to Predict Transcription Factor Binding Sites Using Deep Learning 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2021, 卷号: 18, 期号: 1, 页码: 355-364
作者:  Jing, Fang;  Zhang, Shao-Wu;  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：169/0  |  提交时间：2021/04/26
Bioinformatics  machine learning  transcription factors binding sites  convolutional neural networks  DNA accessibility  histone modification  
TFAP2C-and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment 期刊论文
CELL STEM CELL, 2019, 卷号: 24, 期号: 2, 页码: 271-+
作者:  Li, Lingjie;  Wang, Yong;  Torkelson, Jessica L.;  Shankar, Gautam;  Pattison, Jillian M.;  Zhen, Hanson H.;  Fang, Fengqin;  Duren, Zhana;  Xin, Jingxue;  Gaddam, Sadhana;  Melo, Sandra P.;  Piekos, Samantha N.;  Li, Jiang;  Liaw, Eric J.;  Chen, Lang;  Li, Rui;  Wernig, Marius;  Wong, Wing H.;  Chang, Howard Y.;  Oro, Anthony E.
收藏  |  浏览/下载：282/0  |  提交时间：2019/03/11
Modeling gene regulation from paired expression and chromatin accessibility data 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 25, 页码: E4914-E4923
作者:  Duren, Zhana;  Chen, Xi;  Jiang, Rui;  Wang, Yong;  Wong, Wing Hung
收藏  |  浏览/下载：159/0  |  提交时间：2018/07/30
gene regulation  transcription factor  regulatory element  chromatin regulator  chromatin activity