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BiTSC2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 12
Authors:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
Favorite  |  View/Download:19/0  |  Submit date:2022/06/21
single-cell DNA sequencing  intra-tumor heterogeneity  single nucleotide variation  copy number alteration  Bayesian modeling  cancer evolution  
Identification of Common Driver Gene Modules and Associations between Cancers through Integrated Network Analysis 期刊论文
GLOBAL CHALLENGES, 2021, 页码: 13
Authors:  Gao, Bo;  Zhao, Yue;  Gao, Yonghang;  Li, Guojun;  Wu, Ling-Yun
Favorite  |  View/Download:53/0  |  Submit date:2021/10/26
driver gene module  gene mutation  mutual exclusivity  network analysis  signaling pathway  
RobustClone: a robust PCA method for tumor clone and evolution inference from single-cell sequencing data 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 11, 页码: 3299-3306
Authors:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
Favorite  |  View/Download:80/0  |  Submit date:2020/09/23
Genetic Load and Potential Mutational Meltdown in Cancer Cell Populations 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2019, 卷号: 36, 期号: 3, 页码: 541-552
Authors:  Zhang, Yuezheng;  Li, Yawei;  Li, Tao;  Shen, Xu;  Zhu, Tianqi;  Tao, Yong;  Li, Xueying;  Wang, Di;  Ma, Qin;  Hu, Zheng;  Liu, Jialin;  Ruan, Jue;  Cai, Jun;  Wang, Hurng-Yi;  Lu, Xuemei
Favorite  |  View/Download:106/0  |  Submit date:2020/01/10
genetic load  Muller's ratchet  HeLa cell line  copy number variation  
Stochastic modeling suggests that noise reduces differentiation efficiency by inducing a heterogeneous drug response in glioma differentiation therapy 期刊论文
BMC Systems Biology, 2016, 卷号: 10, 期号: 1
Authors:  Sun,Xiaoqiang;  Zhang,Jiajun;  Zhao,Qi;  Chen,Xing;  Zhu,Wenbo;  Yan,Guangmei;  Zhou,Tianshou
Favorite  |  View/Download:45/0  |  Submit date:2018/07/30
Stochastic modeling  Ultrasensitivity  Noise  Differentiation efficiency  Drug resistance  Glioma differentiation therapy  
Efficient simulation under a population genetics model of carcinogenesis 期刊论文
BIOINFORMATICS, 2011, 卷号: 27, 期号: 6, 页码: 837-843
Authors:  Zhu, Tianqi;  Hu, Yucheng;  Ma, Zhi-Ming;  Zhang, De-Xing;  Li, Tiejun;  Yang, Ziheng
Favorite  |  View/Download:133/0  |  Submit date:2018/07/30