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BiTSC2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 12
作者:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
收藏  |  浏览/下载：158/0  |  提交时间：2022/06/21
single-cell DNA sequencing  intra-tumor heterogeneity  single nucleotide variation  copy number alteration  Bayesian modeling  cancer evolution  
Identification of Common Driver Gene Modules and Associations between Cancers through Integrated Network Analysis 期刊论文
GLOBAL CHALLENGES, 2021, 页码: 13
作者:  Gao, Bo;  Zhao, Yue;  Gao, Yonghang;  Li, Guojun;  Wu, Ling-Yun
收藏  |  浏览/下载：178/0  |  提交时间：2021/10/26
driver gene module  gene mutation  mutual exclusivity  network analysis  signaling pathway  
RobustClone: a robust PCA method for tumor clone and evolution inference from single-cell sequencing data 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 11, 页码: 3299-3306
作者:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
收藏  |  浏览/下载：169/0  |  提交时间：2020/09/23
Genetic Load and Potential Mutational Meltdown in Cancer Cell Populations 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2019, 卷号: 36, 期号: 3, 页码: 541-552
作者:  Zhang, Yuezheng;  Li, Yawei;  Li, Tao;  Shen, Xu;  Zhu, Tianqi;  Tao, Yong;  Li, Xueying;  Wang, Di;  Ma, Qin;  Hu, Zheng;  Liu, Jialin;  Ruan, Jue;  Cai, Jun;  Wang, Hurng-Yi;  Lu, Xuemei
收藏  |  浏览/下载：241/0  |  提交时间：2020/01/10
genetic load  Muller's ratchet  HeLa cell line  copy number variation  
Stochastic modeling suggests that noise reduces differentiation efficiency by inducing a heterogeneous drug response in glioma differentiation therapy 期刊论文
BMC Systems Biology, 2016, 卷号: 10, 期号: 1
作者:  Sun,Xiaoqiang;  Zhang,Jiajun;  Zhao,Qi;  Chen,Xing;  Zhu,Wenbo;  Yan,Guangmei;  Zhou,Tianshou
收藏  |  浏览/下载：126/0  |  提交时间：2018/07/30
Stochastic modeling  Ultrasensitivity  Noise  Differentiation efficiency  Drug resistance  Glioma differentiation therapy  
Efficient simulation under a population genetics model of carcinogenesis 期刊论文
BIOINFORMATICS, 2011, 卷号: 27, 期号: 6, 页码: 837-843
作者:  Zhu, Tianqi;  Hu, Yucheng;  Ma, Zhi-Ming;  Zhang, De-Xing;  Li, Tiejun;  Yang, Ziheng
收藏  |  浏览/下载：197/0  |  提交时间：2018/07/30