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中国科学院数学与系统科学研究院机构知识库
KMS Of Academy of mathematics and systems sciences, CAS
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DATA-ADAPTIVE EFFICIENT ESTIMATION STRATEGIES FOR BIOMARKER STUDIES EMBEDDED IN RANDOMIZED TRIALS
期刊论文
ANNALS OF APPLIED STATISTICS, 2022, 卷号: 16, 期号: 4, 页码: 2250-2265
作者:
Zhang, Weiz
;
Zhang, Zhi wei
;
Troendle, James F.
;
Liu, Aiyi
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/02/07
Augmentation
precision medicine
semiparametric theory
super learner
two-phase sampling
Biomarker interaction selection and disease detection based on multivariate gain ratio
期刊论文
BMC BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 16
作者:
Chu, Xiao
;
Jiang, Mao
;
Liu, Zhuo-Jun
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  |  
浏览/下载:54/0
  |  
提交时间:2023/02/07
Multivariate gain ratio
Biomarker interaction
Disease detection
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:
Lu, Yong
;
Xue, Gang
;
Zheng, Ningbo
;
Han, Kun
;
Yang, Wenzhong
;
Wang, Rui-Sheng
;
Wu, Lingyun
;
Miller, Lance D.
;
Pardee, Timothy
;
Triozzi, Pierre L.
;
Lo, Hui-Wen
;
Watabe, Kounosuke
;
Wong, Stephen T. C.
;
Pasche, Boris C.
;
Zhang, Wei
;
Jin, Guangxu
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  |  
浏览/下载:124/0
  |  
提交时间:2023/02/07
single-cell RNA sequencing (scRNA-seq)
single-cell mass cytometry (CyTOF)
Pareto optimization
projection-free single-cell modeling
response to immune checkpoint blockade
A ROC-based test for evaluating the group difference with an application to neonatal audiology screening
期刊论文
STATISTICS IN MEDICINE, 2021, 页码: 12
作者:
Tang, Larry L.
;
Meng, Zhen
;
Li, Qizhai
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  |  
浏览/下载:146/0
  |  
提交时间:2021/10/26
ROC curve
sensitivity
specificity
two‐
sample comparison
Predicting Brain Regions Related to Alzheimer's Disease Based on Global Feature
期刊论文
FRONTIERS IN COMPUTATIONAL NEUROSCIENCE, 2021, 卷号: 15, 页码: 9
作者:
Wang, Qi
;
Chen, Siwei
;
Wang, He
;
Chen, Luzeng
;
Sun, Yongan
;
Yan, Guiying
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  |  
浏览/下载:143/0
  |  
提交时间:2021/10/26
Alzheimer's disease
diffusion tensor imaging
brain structural network
2hop-connectivity
global featurescore
differential network analysis
Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies
期刊论文
BMC MEDICAL RESEARCH METHODOLOGY, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:
Zhang, Wei
;
Zhang, Zhiwei
;
Krushkal, Julia
;
Liu, Aiyi
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浏览/下载:134/0
  |  
提交时间:2021/04/26
Biomarker study design
Cost-efficiency
Group testing
Pooling
Two-phase sampling
Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard
期刊论文
STATISTICS IN MEDICINE, 2020, 页码: 25
作者:
Wu, Mixia
;
Zhang, Xiaoyu
;
Zhang, Wei
;
Zhang, Xu
;
Liu, Aiyi
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  |  
浏览/下载:131/0
  |  
提交时间:2021/01/14
adaptive estimation
additive errors
asymptotic normality
biomarkers
diagnostic accuracy
measurement errors
reliability coefficient
A Branch Point on Differentiation Trajectory is the Bifurcating Event Revealed by Dynamical Network Biomarker Analysis of Single-Cell Data
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 366-375
作者:
Chen, Ziwei
;
Bai, Xiangqi
;
Ma, Liang
;
Wang, Xiawei
;
Liu, Xiuqin
;
Liu, Yuting
;
Chen, Luonan
;
Wan, Lin
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  |  
浏览/下载:175/0
  |  
提交时间:2020/05/24
Trajectory
Heuristic algorithms
Mice
Correlation
Reactive power
Pseudo temporal trajectory
branch point
DNB theory
reconstruction
single-cell data
bifurcation
dynamical system
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:
Sun, Duanchen
;
Ren, Xianwen
;
Ari, Eszter
;
Korcsmaros, Tamas
;
Csermely, Peter
;
Wu, Ling-Yun
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  |  
浏览/下载:291/0
  |  
提交时间:2019/03/05
heterogeneous diseases
cancer biomarker
network-based
cooperative biomarker
gene expression
Network-Regularized Sparse Logistic Regression Models for Clinical Risk Prediction and Biomarker Discovery
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 944-953
作者:
Min, Wenwen
;
Liu, Juan
;
Zhang, Shihua
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  |  
浏览/下载:250/0
  |  
提交时间:2018/07/30
Sparse logistic regression
network-regularized penalty
survival risk prediction
feature selection