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Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
Authors:  Shi, Xiaohan;  Li, Yunguang;  Yuan, Qiuyue;  Tang, Shijie;  Guo, Shiwei;  Zhang, Yehan;  He, Juan;  Zhang, Xiaoyu;  Han, Ming;  Liu, Zhuang;  Zhu, Yiqin;  Gao, Suizhi;  Wang, Huan;  Xu, Xiongfei;  Zheng, Kailian;  Jing, Wei;  Chen, Luonan;  Wang, Yong;  Jin, Gang;  Gao, Dong
Favorite  |  View/Download:33/0  |  Submit date:2022/06/21
Article The cell-surface 5 '-nucleotidase CD73 defines a functional T memory cell subset that declines with age 期刊论文
CELL REPORTS, 2021, 卷号: 37, 期号: 6, 页码: 24
Authors:  Fang, Fengqin;  Cao, Wenqiang;  Zhu, Weikang;  Lam, Nora;  Li, Lingjie;  Gaddam, Sadhana;  Wang, Yong;  Kim, Chulwoo;  Lambert, Simon;  Zhang, Huimin;  Hu, Bin;  Farber, Donna L.;  Weyand, Cornelia M.;  Goronzy, Jorg J.
Favorite  |  View/Download:45/0  |  Submit date:2022/04/02
OpenAnnotate: a web server to annotate the chromatin accessibility of genomic regions 期刊论文
NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: W1, 页码: W483-W490
Authors:  Chen, Shengquan;  Liu, Qiao;  Cui, Xuejian;  Feng, Zhanying;  Li, Chunquan;  Wang, Xiaowo;  Zhang, Xuegong;  Wang, Yong;  Jiang, Rui
Favorite  |  View/Download:53/0  |  Submit date:2021/10/26
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3, 页码: 15
Authors:  Dong, Kangning;  Zhang, Shihua
Favorite  |  View/Download:40/0  |  Submit date:2022/04/02
cis-regulatory interaction networks  single-cell ATAC-seq  Gaussian graphical LASSO  
hReg-CNCC reconstructs a regulatory network in human cranial neural crest cells and annotates variants in a developmental context 期刊论文
COMMUNICATIONS BIOLOGY, 2021, 卷号: 4, 期号: 1, 页码: 16
Authors:  Feng, Zhanying;  Duren, Zhana;  Xiong, Ziyi;  Wang, Sijia;  Liu, Fan;  Wong, Wing Hung;  Wang, Yong
Favorite  |  View/Download:77/0  |  Submit date:2021/06/01
An Integrative Framework for Combining Sequence and Epigenomic Data to Predict Transcription Factor Binding Sites Using Deep Learning 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2021, 卷号: 18, 期号: 1, 页码: 355-364
Authors:  Jing, Fang;  Zhang, Shao-Wu;  Cao, Zhen;  Zhang, Shihua
Favorite  |  View/Download:78/0  |  Submit date:2021/04/26
Bioinformatics  machine learning  transcription factors binding sites  convolutional neural networks  DNA accessibility  histone modification  
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 20
Authors:  Xin, Jingxue;  Zhang, Hui;  He, Yaoxi;  Duren, Zhana;  Bai, Caijuan;  Chen, Lang;  Luo, Xin;  Yan, Dong-Sheng;  Zhang, Chaoyu;  Zhu, Xiang;  Yuan, Qiuyue;  Feng, Zhanying;  Cui, Chaoying;  Qi, Xuebin;  Ouzhuluobu;  Wong, Wing Hung;  Wang, Yong;  Su, Bing
Favorite  |  View/Download:74/0  |  Submit date:2021/01/14
Time course regulatory analysis based on paired expression and chromatin accessibility data 期刊论文
GENOME RESEARCH, 2020, 卷号: 30, 期号: 4, 页码: 622-634
Authors:  Duren, Zhana;  Chen, Xi;  Xin, Jingxue;  Wang, Yong;  Wong, Wing Hung
Favorite  |  View/Download:94/0  |  Submit date:2020/06/30
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 11
Authors:  Zeng, Wanwen;  Chen, Xi;  Duren, Zhana;  Wang, Yong;  Jiang, Rui;  Wong, Wing Hung
Favorite  |  View/Download:109/0  |  Submit date:2020/01/10
TFAP2C-and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment 期刊论文
CELL STEM CELL, 2019, 卷号: 24, 期号: 2, 页码: 271-+
Authors:  Li, Lingjie;  Wang, Yong;  Torkelson, Jessica L.;  Shankar, Gautam;  Pattison, Jillian M.;  Zhen, Hanson H.;  Fang, Fengqin;  Duren, Zhana;  Xin, Jingxue;  Gaddam, Sadhana;  Melo, Sandra P.;  Piekos, Samantha N.;  Li, Jiang;  Liaw, Eric J.;  Chen, Lang;  Li, Rui;  Wernig, Marius;  Wong, Wing H.;  Chang, Howard Y.;  Oro, Anthony E.
Favorite  |  View/Download:163/0  |  Submit date:2019/03/11